Medicine detail

Acetaminophen, diphenhydramine hcl

Used for: temporary relief of occasional headaches and minor aches and pains with accompanying sleeplessness

Catalog search

Analgesic, antipyretic, or anti-inflammatory medicine Pain and fever ID 1385

acetaminophen, diphenhydramine hcl reference image: A weekly medication organizer with capsules. — Image: Pilulier semainier.JPG by Stephane8888, CC BY-SA 2.5.

What It Is Used For

Used for: temporary relief of occasional headaches and minor aches and pains with accompanying sleeplessness

openFDA drug label

Active Ingredient

ACETAMINOPHEN, DIPHENHYDRAMINE HCL

Chemical Name

ACETAMINOPHEN, DIPHENHYDRAMINE HCL

Common Brands

Pain Reliever PM Extra Strength

Generic / Alternate Names

ACETAMINOPHEN, DIPHENHYDRAMINE HCL

Tracking Note

Use this entry as a reference/search starting point; verify dose, indication, and safety details with official labeling or a clinician.

Reference Links

RxNorm PubChem DailyMed MedlinePlus PubMed Studies

Clinical links

Linked conditions and symptoms

Allergies reference image: An anatomical illustration of red blood cells. — Image: Blausen 0761 RedBloodCells.png by BruceBlaus, CC BY 3.0.

Allergies

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Blood / immune common use

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Anaphylaxis reference image: An anatomical illustration of red blood cells. — Image: Blausen 0761 RedBloodCells.png by BruceBlaus, CC BY 3.0.

Anaphylaxis

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Blood / immune common use

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Pain and Inflammation reference image: A weekly medication organizer with capsules. — Image: Pilulier semainier.JPG by Stephane8888, CC BY-SA 2.5.

Pain and Inflammation

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

General Medicine common use

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Chronic Pain reference image: A weekly medication organizer with capsules. — Image: Pilulier semainier.JPG by Stephane8888, CC BY-SA 2.5.

Chronic Pain

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

General medicine common use

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Fever reference image: A weekly medication organizer with capsules. — Image: Pilulier semainier.JPG by Stephane8888, CC BY-SA 2.5.

Fever

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

General medicine common use

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Bipolar Disorder reference image: An anatomical illustration of the brain. — Image: Blausen 0101 Brain LateralView.png by BruceBlaus, CC BY 3.0.

Bipolar Disorder

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Mental health common use

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Back Pain reference image: An anatomical illustration of the knee joint. — Image: Blausen 0596 KneeAnatomy Front.png by BruceBlaus, CC BY 3.0.

Back Pain

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Musculoskeletal / rheumatology common use

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Fibromyalgia reference image: An anatomical illustration of the knee joint. — Image: Blausen 0596 KneeAnatomy Front.png by BruceBlaus, CC BY 3.0.

Fibromyalgia

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Musculoskeletal / rheumatology common use

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Osteoarthritis reference image: An anatomical illustration of the knee joint. — Image: Blausen 0596 KneeAnatomy Front.png by BruceBlaus, CC BY 3.0.

Osteoarthritis

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Musculoskeletal / rheumatology common use

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Epilepsy reference image: An anatomical illustration of the brain. — Image: Blausen 0101 Brain LateralView.png by BruceBlaus, CC BY 3.0.

Epilepsy

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Neurologic common use

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Migraine reference image: An anatomical illustration of the brain. — Image: Blausen 0101 Brain LateralView.png by BruceBlaus, CC BY 3.0.

Migraine

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Neurologic common use

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Neuropathy reference image: An anatomical illustration of the brain. — Image: Blausen 0101 Brain LateralView.png by BruceBlaus, CC BY 3.0.

Neuropathy

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Neurologic common use

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Restless Legs Syndrome reference image: An anatomical illustration of the brain. — Image: Blausen 0101 Brain LateralView.png by BruceBlaus, CC BY 3.0.

Restless Legs Syndrome

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Neurologic common use

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Allergic Rhinitis reference image: An anatomical illustration of red blood cells. — Image: Blausen 0761 RedBloodCells.png by BruceBlaus, CC BY 3.0.

Allergic Rhinitis

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Respiratory common use

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Eczema reference image: An anatomical illustration of skin layers. — Image: Blausen 0810 SkinAnatomy 01.png by BruceBlaus, CC BY 3.0.

Eczema

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Skin / dermatology common use

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Hives reference image: An anatomical illustration of skin layers. — Image: Blausen 0810 SkinAnatomy 01.png by BruceBlaus, CC BY 3.0.

Hives

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Skin / dermatology common use

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Tongue swelling reference image: An anatomical illustration of the human heart. — Image: Blausen 0451 Heart Anterior.png by Blausen Medical Communications, Inc., CC BY 3.0.

Tongue swelling

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Eye / ear / nose / throat symptom context

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Watery eyes reference image: A person jogging outdoors. — Image: Jogging Woman in Grass.jpg by Mike Baird, CC BY 2.0.

Watery eyes

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Eye / ear / nose / throat symptom context

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Fever reference image: A person jogging outdoors. — Image: Jogging Woman in Grass.jpg by Mike Baird, CC BY 2.0.

Fever

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

General / systemic symptom context

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Swelling reference image: An anatomical illustration of the human heart. — Image: Blausen 0451 Heart Anterior.png by Blausen Medical Communications, Inc., CC BY 3.0.

Swelling

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

General / systemic symptom context

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Severe allergic reaction reference image: A weekly medication organizer with capsules. — Image: Pilulier semainier.JPG by Stephane8888, CC BY-SA 2.5.

Severe allergic reaction

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Medication / allergy symptom context

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Back pain reference image: An anatomical illustration of the knee joint. — Image: Blausen 0596 KneeAnatomy Front.png by BruceBlaus, CC BY 3.0.

Back pain

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Pain symptom context

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Cramps reference image: A person jogging outdoors. — Image: Jogging Woman in Grass.jpg by Mike Baird, CC BY 2.0.

Cramps

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Pain symptom context

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Headache reference image: An anatomical illustration of the brain. — Image: Blausen 0101 Brain LateralView.png by BruceBlaus, CC BY 3.0.

Headache

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Pain symptom context

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Joint pain reference image: An anatomical illustration of the knee joint. — Image: Blausen 0596 KneeAnatomy Front.png by BruceBlaus, CC BY 3.0.

Joint pain

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Pain symptom context

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Muscle pain reference image: An anatomical illustration of the knee joint. — Image: Blausen 0596 KneeAnatomy Front.png by BruceBlaus, CC BY 3.0.

Muscle pain

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Pain symptom context

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Neck pain reference image: A person jogging outdoors. — Image: Jogging Woman in Grass.jpg by Mike Baird, CC BY 2.0.

Neck pain

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Pain symptom context

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Pain reference image: A person jogging outdoors. — Image: Jogging Woman in Grass.jpg by Mike Baird, CC BY 2.0.

Pain

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Pain symptom context

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Severe headache reference image: An anatomical illustration of the brain. — Image: Blausen 0101 Brain LateralView.png by BruceBlaus, CC BY 3.0.

Severe headache

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Pain symptom context

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Severe pain reference image: A person jogging outdoors. — Image: Jogging Woman in Grass.jpg by Mike Baird, CC BY 2.0.

Severe pain

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Pain symptom context

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Toothache reference image: A person jogging outdoors. — Image: Jogging Woman in Grass.jpg by Mike Baird, CC BY 2.0.

Toothache

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Pain symptom context

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Nasal congestion reference image: An anatomical illustration of the respiratory system. — Image: Blausen 0770 RespiratorySystem 02.png by BruceBlaus, CC BY 3.0.

Nasal congestion

Commonly used in pain, fever, or inflammation care depending on formulation and patient-specific indication.

Respiratory symptom context

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